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Ketosis occurs when the body burns fat for energy, commonly leading to a sweet, acetone-like odor in the breath, McGowan says
TOPCAT studied the impact of spironolactone on cardiovascular death, cardiac arrest and HF hospitalizations in patients with HFpEF
Cardiovascular risk reduction with icosapent ethyl for hypertriglyceridemia
other lymphadenopathy persisting for 4-6 weeks Progressive growth : Nodes that continue to increase in size over time Hard, fixed, or irregular nodes : Lymph nodes that feel firm, immobile, or have an irregular texture may indicate serious pathology Generalised lymphadenopathy : Swelling in multiple lymph node regions (neck, armpits, groin) simultaneously Systemic symptoms : Unexplained fever, drenching night sweats, unintentional weight loss (beyond expected GLP-1-related weight reduction), or persistent fatigue Associated symptoms : Difficulty swallowing, breathing difficulties, or hoarseness accompanying neck lymphadenopathy According to NICE guideline NG12 , lymphadenopathy with concerning features should prompt consideration of a suspected cancer pathway referral (2-week wait)
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