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Direct Anti-Fibrotic Mechanisms In considering the direct anti-fibrotic mechanisms, it is important to note that the expression of incretin receptors is not confined to the pancreatic islets

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Calcitonin , the 32 amino acid peptide secreted from the C cells of the thyroid gland, appears to inhibit the stimulated secretion of GH by GHRH, arginine, and insulin-induced hypoglycemia (422,423)