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Likewise, restraint stress rapidly modulated KP enzyme expression in rats, with amygdala IDO increasing within 1 h, amygdala KMO and kynureninase rising by 4 h, hippocampal TDO decreasing within 4 h, hypothalamic TDO upregulated at 4 h, and medial prefrontal cortex kynureninase reduced shortly after stress with effects lasting at least 24 h [70]

Consensus docking and induced-fit docking further identified a thermodynamically favorable and stable TMLSLC25A45 complex, with TML adopting a conformation well accommodated within the channel cavity

Urban, Meyrin (Cardiologie)

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