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In particular, hippocampal damage is correlated with memory impairment and learning difficulties, whereas prefrontal atrophy contributes to deficits in executive function and increased impulsivity
These inadequacies emphasize the need for a more comprehensive, unifying mechanism to elucidate the complex relationship between CVDs and cognitive impairment at cellular and molecular levels, and underscore the urgency of further research into mitochondrias role in this comorbidity
In addition, S -nitrosylation of the Cys215 residue by NO donors shields PTP1B from subsequent hydrogen peroxide-induced irreversible oxidation (88)