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Those included also had no dispensing of the qualifying opioids in the previous 6 months

In May 2026, At the EASL Congress 2026, MetaVia presented promising late-breaking Phase 1 clinical trial results for DA-1726, an investigational dual GLP-1 and glucagon receptor agonist under development for obesity and Metabolic Dysfunction-Associated Steatohepatitis (MASH)

Excess free radical production can be triggered by a variety of external factors, each of which effectively disrupts the oxidant-antioxidant balance in the body

However, combination with insulin or sulfonylureas requires dose adjustment to prevent hypoglycemia