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However, the injection, which also helps people manage their diabetes, is fraught with side effects, some of which are deadly or cause patients to become suddenly and permanently blind

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Tirzepatide pros Effective for weight loss : Tirzepatide has shown significant weight loss results, with some patients losing over 20% of their body weight, especially in people with obesity

CagriSema (the combination) was submitted for FDA approval in December 2025, but cagrilintide on its own is earlier in the process