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Further research found that GA can reverse the decline of peroxisome proliferator-activated receptor alpha (PPAR-) and liver X receptor-alpha (LXR-) and the increase of sterol regulatory element-binding protein-1c (SREBP-1c) mRNA caused by HFD by anti-oxidative stress and improving steatopathy, thus alleviating NAFLD ( GA has the potential to alleviate NAFLD via the AMPK pathway, subsequently hindering the progression to hepatitis and cirrhosis, thereby underscoring AMPK as a crucial therapeutic target

Chadchan SB, Naik SK, Popli P, Talwar C, Putluri S, Ambati CR, Lint MA, Kau AL, Stallings CL, Kommagani R

For example, the HRV 3C protease recognizes and cleaves the sequence Leu-Glu-Val-Leu-Phe-Gln--Gly-Pro, enabling the separation of the GST tag from the target protein

Fulgente T, Onofrj M, Delre M, et al