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Practically, this means the peptides distribution and the coppers ultimate fate are dominated by whole-body copper homeostasis hepatic uptake, biliary excretion (the principal route by which the body eliminates excess copper), and the binding capacity of plasma proteins rather than by the peptide behaving as an independent, freely distributing drug
Free fatty acid receptor GPR120 is highly expressed in enteroendocrine K cells of the upper small intestine and has a critical role in GIP secretion after fat ingestion
doi: 10.1016/j.molmed.2006.07.008 118 GarrawayLAWidlundHRRubinMAGetzGBergerAJRamaswamySet al
Nrf2 deficiency predisposes mice to noise-induced microglial deramification in the auditory cortex Neuroinflammation in the auditory cortex has been linked to the development of tinnitus in rodent models 9
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