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Fsp1 knockout enhanced CaOX-induced ferroptosis in MTECs To further investigate the role of Fsp1 in oxalate-induced AKI, the CRISPR-Cas9 system was employed to create Fsp1 knockout MTECs and confirmed through Sanger sequencing and Western blot analysis (Fig

Two protein families are mostly used in targeted therapy: (1) designed ankyrin repeat proteins (DARPins), a type of non-immunoglobulin-engineered protein derived from the ankyrin protein and (2) macrocyclic peptides produced by the random non-standard peptides integrated discovery (RaPID) system

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