Contract research organizations (CROs) use it as a standard to see how well HPLC and mass spectrometry methods work
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These include some heartburn medicines, including esomeprazole (Nexium), famotidine (Pepcid AC), lansoprazole (Prevacid), omeprazole (Prilosec OTC), pantoprazole (Protonix), rabeprazole (Aciphex), as well as some diabetes, gout, and chemotherapy drugs
Some people notice improvements within a few weeks, while others may require several months of consistent treatment