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Conclusion: Long-term randomized placebo-controlled trials with larger sample sizes are needed to provide stronger evidence on the long-term efficacy and safety of semaglutide for obesity treatment in PWS as well as explore the potential synergistic effects of GLP-1 RA treatment combined with other therapeutic interventions

Autocorrelation curves were modelled in Zen 2012 (Carl Zeiss, Jena) to describe a single 3D diffusing component under free diffusion (Corriden 2014)

Individually, semaglutide has been found to be noninferior to placebo when examining rates of cardiovascular death, nonfatal myocardial infarction, or nonfatal stroke in patients with type 2 diabetes at high cardiovascular risk 18,19

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