fasting on tirzepatide Day 3: Mounjaro (Tirzepatide – weekly injection) Class: Dual GLP-1 and GIP receptor agonist Avg Weight Loss: ~20% of baseline weight (SURMOUNT-1 trial) FDA Status: Approved for type 2 diabetes; Fast-tracked for After starting Mounjaro (Tirzepatide), many

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Intermittent Treatment Strategies Many patients and providers now discuss whether GLP-1 therapy should continue long-term or cycle intermittently based on individual metabolic stability, weight regain rate, and treatment tolerance

However, states are simultaneously experiencing several significant upward expenditure pressures that outweigh the downward pressure from enrollment trends, causing increases in total Medicaid spending (and as a result, spending per enrollee): Over half of responding states cited managed care or provider rate increases as an upward pressure on total spending in FY 2025, FY 2026, or both