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Similar to the observations for sweet taste, a number of studies point towards a decreased threshold for bitter taste [8688] while others were not able to demonstrate any change of this taste quality upon weight loss [85]

Comprehensive assessment is always preferable to self-management when digestive symptoms persist or cause concern

0.6mg dose: 6.2% average weight loss 2.4mg dose: 12.5% average weight loss 3.6mg dose: 13.2% average weight loss 4.8mg dose: 14.9% average weight loss (planned treatment analysis) 4.8mg dose: 18.7% average weight loss (actual treatment received analysis) Placebo: 2.8% average weight loss The distinction between planned treatment and actual treatment received analyses matters