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SGLT2 vs Dual Agonists: Putting Weight Loss in Context SGLT2 inhibitors like empagliflozin (Jardiance) offer modest weight reduction of approximately 4 to 6 pounds, a fraction of what dual agonists deliver

Myocardial T2* improved from 12.5 ms to 30 ms, indicating a marked reduction in myocardial iron loading (Figure 9C)

Cycling Preserves Sensitivity Periodic breaks from the protocol prevent potential receptor desensitization that could reduce effectiveness over time

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